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A New Model for Pore Formation by Cholesterol-Dependent Cytolysins

Cholesterol Dependent Cytolysins (CDCs) are important bacterial virulence factors that form large (200–300 Å) membrane embedded pores in target cells. Currently, insights from X-ray crystallography, biophysical and single particle cryo-Electron Microscopy (cryo-EM) experiments suggest that soluble m...

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Detalhes bibliográficos
Main Authors: Reboul, Cyril F., Whisstock, James C., Dunstone, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140638/
https://ncbi.nlm.nih.gov/pubmed/25144725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003791
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