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Effect of the English Familial Disease Mutation (H6R) on the Monomers and Dimers of Aβ40 and Aβ42

[Image: see text] The self-assembly of the amyloid beta (Aβ) peptides into senile plaques is the hallmark of Alzheimer’s disease. Recent experiments have shown that the English familial disease mutation (H6R) speeds up the fibril formation process of alloforms Aβ(40) and Aβ(42) peptides altering the...

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書誌詳細
主要な著者: Viet, Man Hoang, Nguyen, Phuong H., Derreumaux, Philippe, Li, Mai Suan
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140585/
https://ncbi.nlm.nih.gov/pubmed/24949887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500007j
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