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Effect of the English Familial Disease Mutation (H6R) on the Monomers and Dimers of Aβ40 and Aβ42

[Image: see text] The self-assembly of the amyloid beta (Aβ) peptides into senile plaques is the hallmark of Alzheimer’s disease. Recent experiments have shown that the English familial disease mutation (H6R) speeds up the fibril formation process of alloforms Aβ(40) and Aβ(42) peptides altering the...

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Detalhes bibliográficos
Main Authors: Viet, Man Hoang, Nguyen, Phuong H., Derreumaux, Philippe, Li, Mai Suan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140585/
https://ncbi.nlm.nih.gov/pubmed/24949887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500007j
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