A carregar...

Conformational Ensembles of the Wild-Type and S8C Aβ1–42 Dimers

We characterized the dimer of the amyloid-β wild-type (WT) peptide, Aβ, of 42 residues and its disulfide-bond-locked double mutant (S8C) by replica exchange molecular dynamics simulations. Aβ dimers are known to be the smallest toxic species in Alzheimer’s disease, and the S8C mutant has been shown...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Man, Viet Hoang, Nguyen, Phuong H., Derreumaux, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5944329/
https://ncbi.nlm.nih.gov/pubmed/28245647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00267
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!