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Effect of the Tottori Familial Disease Mutation (D7N) on the Monomers and Dimers of Aβ(40) and Aβ(42)
[Image: see text] Recent experiments have shown that the mutation Tottori (D7N) alters the toxicity, assembly and rate of fibril formation of the wild type (WT) amyloid beta (Aβ) Aβ(40) and Aβ(42) peptides. We used all-atom molecular dynamics simulations in explicit solvent of the monomer and dimer...
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| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837376/ https://ncbi.nlm.nih.gov/pubmed/24041307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400110d |
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