Načítá se...
Conformational Ensembles of the Wild-Type and S8C Aβ1–42 Dimers
We characterized the dimer of the amyloid-β wild-type (WT) peptide, Aβ, of 42 residues and its disulfide-bond-locked double mutant (S8C) by replica exchange molecular dynamics simulations. Aβ dimers are known to be the smallest toxic species in Alzheimer’s disease, and the S8C mutant has been shown...
Uloženo v:
| Vydáno v: | J Phys Chem B |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5944329/ https://ncbi.nlm.nih.gov/pubmed/28245647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b00267 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|