Regulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes

Inappropriate activation of cell cycle proteins, in particular cyclin D/Cdk4, is implicated in neuronal death induced by various pathologic stresses, including DNA damage and ischemia. Key targets of Cdk4 in proliferating cells include members of the E2F transcription factors, which mediate the expr...

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Detalhes bibliográficos
Main Authors: Iyirhiaro, Grace O., Zhang, Yi, Estey, Carmen, O'Hare, Michael J., Safarpour, Farzaneh, Parsanejad, Mohammad, Wang, Suzi, Abdel-Messih, Elizabeth, Callaghan, Steve M., During, Matthew J., Slack, Ruth S., Park, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140295/
https://ncbi.nlm.nih.gov/pubmed/24828495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574145
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