Regulation of Ischemic Neuronal Death by E2F4-p130 Protein Complexes

Inappropriate activation of cell cycle proteins, in particular cyclin D/Cdk4, is implicated in neuronal death induced by various pathologic stresses, including DNA damage and ischemia. Key targets of Cdk4 in proliferating cells include members of the E2F transcription factors, which mediate the expr...

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Hauptverfasser: Iyirhiaro, Grace O., Zhang, Yi, Estey, Carmen, O'Hare, Michael J., Safarpour, Farzaneh, Parsanejad, Mohammad, Wang, Suzi, Abdel-Messih, Elizabeth, Callaghan, Steve M., During, Matthew J., Slack, Ruth S., Park, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140295/
https://ncbi.nlm.nih.gov/pubmed/24828495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574145
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