DNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases

DNA topoisomerases control the topology of DNA. Type II topoisomerases exhibit topology simplification, whereby products of their reactions are simplified beyond that expected based on thermodynamic equilibrium. The molecular basis for this process is unknown, although DNA bending has been implicate...

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Bibliographic Details
Main Authors: Thomson, Neil H., Santos, Sergio, Mitchenall, Lesley A., Stuchinskaya, Tanya, Taylor, James A., Maxwell, Anthony
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139952/
https://ncbi.nlm.nih.gov/pubmed/25142513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06158
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