How do type II topoisomerases use ATP hydrolysis to simplify DNA topology beyond equilibrium? Investigating the relaxation reaction of non-supercoiling type II topoisomerases

DNA topoisomerases control the topology of DNA (e.g. the level of supercoiling) in all cells. Type IIA topoisomerases are ATP-dependent enzymes that have been shown to simplify the topology of their DNA substrates to a level beyond that expected at equilibrium (i.e. more relaxed than the product of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Stuchinskaya, Tanya, Mitchenall, Lesley A., Schoeffler, Allyn J., Corbett, Kevin D., Berger, James M., Bates, Andrew D., Maxwell, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343537/
https://ncbi.nlm.nih.gov/pubmed/19094994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.11.056
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker