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The Effect of Dimethyl Sulfoxide on Supercoiled DNA Relaxation Catalyzed by Type I Topoisomerases

The effects of dimethyl sulfoxide (DMSO) on supercoiled plasmid DNA relaxation catalyzed by two typical type I topoisomerases were investigated in our studies. It is shown that DMSO in a low concentration (less than 20%, v/v) can induce a dose-related enhancement of the relaxation efficiency of Esch...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Lv, Bei, Dai, Yunjia, Liu, Ju, Zhuge, Qiang, Li, Dawei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670693/
https://ncbi.nlm.nih.gov/pubmed/26682217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/320490
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