Bacterial topoisomerase I and topoisomerase III relax supercoiled DNA via distinct pathways

Escherichia coli topoisomerases I and III (Topo I and Topo III) relax negatively supercoiled DNA and also catenate/decatenate DNA molecules containing single-stranded DNA regions. Although these enzymes share the same mechanism of action and have similar structures, they participate in different cel...

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Bibliographic Details
Main Authors: Terekhova, Ksenia, Gunn, Kathryn H., Marko, John F., Mondragón, Alfonso
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488232/
https://ncbi.nlm.nih.gov/pubmed/22923519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks780
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