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Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors
Urea transport (UT) proteins of the UT-A class are expressed in epithelial cells in kidney tubules, where they are required for the formation of a concentrated urine by countercurrent multiplication. Here, using a recently developed high-throughput assay to identify UT-A inhibitors, a screen of 50,0...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Federation of American Societies for Experimental Biology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139901/ https://ncbi.nlm.nih.gov/pubmed/24843071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-253872 |
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