A carregar...
Discovery, synthesis and structure-activity analysis of symmetrical 2,7-disubstituted fluorenones as urea transporter inhibitors
Kidney urea transporters are targets for development of small-molecule inhibitors with action as salt-sparing diuretics. A cell-based, functional high-throughput screen identified 2,7-bisacetamido fluorenone 3 as a novel inhibitor of urea transporters UT-A1 and UT-B. Here, we synthesized twenty-two...
Na minha lista:
| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501499/ https://ncbi.nlm.nih.gov/pubmed/26191399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C5MD00198F |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|