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Functional Roles of the Dimer-Interface Residues in Human Ornithine Decarboxylase

Ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine to putrescine and is the rate-limiting enzyme in the polyamine biosynthesis pathway. ODC is a dimeric enzyme, and the active sites of this enzyme reside at the dimer interface. Once the enzyme dissociates, the enzyme activity i...

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Detalhes bibliográficos
Main Authors: Lee, Chien-Yun, Liu, Yi-Liang, Lin, Chih-Li, Liu, Guang-Yaw, Hung, Hui-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139326/
https://ncbi.nlm.nih.gov/pubmed/25140796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104865
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