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Functional Roles of the Dimer-Interface Residues in Human Ornithine Decarboxylase
Ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine to putrescine and is the rate-limiting enzyme in the polyamine biosynthesis pathway. ODC is a dimeric enzyme, and the active sites of this enzyme reside at the dimer interface. Once the enzyme dissociates, the enzyme activity i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139326/ https://ncbi.nlm.nih.gov/pubmed/25140796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104865 |
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