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Excision of Uracil from Transcribed DNA Negatively Affects Gene Expression
Uracil is an unavoidable aberrant base in DNA, the repair of which takes place by a highly efficient base excision repair mechanism. The removal of uracil from the genome requires a succession of intermediate products, including an abasic site and a single strand break, before the original DNA struc...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139217/ https://ncbi.nlm.nih.gov/pubmed/24951587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521807 |
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