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Cockayne Syndrome: Varied Requirement of Transcription-Coupled Nucleotide Excision Repair for the Removal of Three Structurally Different Adducts from Transcribed DNA

Hereditary defects in the transcription-coupled nucleotide excision repair (TC-NER) pathway of damaged DNA cause severe neurodegenerative disease Cockayne syndrome (CS), however the origin and chemical nature of the underlying DNA damage had remained unknown. To find out, to which degree the structu...

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Detalhes bibliográficos
Main Authors: Kitsera, Nataliya, Gasteiger, Karola, Lühnsdorf, Bork, Allgayer, Julia, Epe, Bernd, Carell, Thomas, Khobta, Andriy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979923/
https://ncbi.nlm.nih.gov/pubmed/24713864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094405
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