Llwytho...

8-Oxo-7,8-dihydroguanine in DNA does not constitute a barrier to transcription, but is converted into transcription-blocking damage by OGG1

The common DNA base modification 8-oxo-7,8-dihydroguanine (8-oxo-G) affects the efficiency and fidelity of transcription. We constructed plasmid substrates carrying single 8-oxo-G residues, specifically positioned in the transcribed or the non-transcribed DNA strands, to investigate their effects on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kitsera, Nataliya, Stathis, Dimitrios, Lühnsdorf, Bork, Müller, Heiko, Carell, Thomas, Epe, Bernd, Khobta, Andriy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152326/
https://ncbi.nlm.nih.gov/pubmed/21441539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr163
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!