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Cockayne Syndrome: Varied Requirement of Transcription-Coupled Nucleotide Excision Repair for the Removal of Three Structurally Different Adducts from Transcribed DNA

Hereditary defects in the transcription-coupled nucleotide excision repair (TC-NER) pathway of damaged DNA cause severe neurodegenerative disease Cockayne syndrome (CS), however the origin and chemical nature of the underlying DNA damage had remained unknown. To find out, to which degree the structu...

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Bibliografski detalji
Glavni autori: Kitsera, Nataliya, Gasteiger, Karola, Lühnsdorf, Bork, Allgayer, Julia, Epe, Bernd, Carell, Thomas, Khobta, Andriy
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979923/
https://ncbi.nlm.nih.gov/pubmed/24713864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094405
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