Cockayne Syndrome: Varied Requirement of Transcription-Coupled Nucleotide Excision Repair for the Removal of Three Structurally Different Adducts from Transcribed DNA

Hereditary defects in the transcription-coupled nucleotide excision repair (TC-NER) pathway of damaged DNA cause severe neurodegenerative disease Cockayne syndrome (CS), however the origin and chemical nature of the underlying DNA damage had remained unknown. To find out, to which degree the structu...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kitsera, Nataliya, Gasteiger, Karola, Lühnsdorf, Bork, Allgayer, Julia, Epe, Bernd, Carell, Thomas, Khobta, Andriy
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979923/
https://ncbi.nlm.nih.gov/pubmed/24713864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094405
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