Highly Multiplexed and Reproducible Ion-Current-Based Strategy for Large-Scale Quantitative Proteomics and the Application to Protein Expression Dynamics Induced by Methylprednisolone in 60 Rats

[Image: see text] A proteome-level time-series study of drug effects (i.e., pharmacodynamics) is critical for understanding mechanisms of action and systems pharmacology, but is challenging, because of the requirement of a proteomics method for reliable quantification of many biological samples. Her...

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Main Authors: Nouri-Nigjeh, Eslam, Sukumaran, Siddharth, Tu, Chengjian, Li, Jun, Shen, Xiaomeng, Duan, Xiaotao, DuBois, Debra C., Almon, Richard R., Jusko, William J., Qu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139173/
https://ncbi.nlm.nih.gov/pubmed/25072516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac501380s
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