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A Microarray Analysis of the Temporal Response of Liver to Methylprednisolone: A Comparative Analysis of Two Dosing Regimens

Microarray analyses were performed on livers from adrenalectomized male Wistar rats chronically infused with methylprednisolone (MPL) (0.3 mg/kg·h) using Alzet mini-osmotic pumps for periods ranging from 6 h to 7 d. Four control and 40 drug-treated animals were killed at 10 different times during dr...

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Bibliographic Details
Main Authors: Almon, Richard R., DuBois, Debra C., Jusko, William J.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183266/
https://ncbi.nlm.nih.gov/pubmed/17303664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2006-0790
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