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The genomic response of skeletal muscle to methylprednisolone using microarrays: tailoring data mining to the structure of the pharmacogenomic time series

High-throughput data collection using gene microarrays has great potential as a method for addressing the pharmacogenomics of complex biological systems. Similarly, mechanism-based pharmacokinetic/pharmacodynamic modeling provides a tool for formulating quantitative testable hypotheses concerning th...

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Bibliographic Details
Main Authors: Almon, Richard R, DuBois, Debra C, Piel, William H, Jusko, William J
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607486/
https://ncbi.nlm.nih.gov/pubmed/15212590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14622416.5.5.525
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