Immunodominance and functional alterations of tumor‐associated antigen‐specific CD8(+) T‐cell responses in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide with a poor prognosis and limited therapeutic options. To aid the development of novel immunological interventions, we studied the breadth, frequency, and tumor‐infiltration of naturally occurring CD8(+) T‐cell responses ta...

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Detalhes bibliográficos
Main Authors: Flecken, Tobias, Schmidt, Nathalie, Hild, Sandra, Gostick, Emma, Drognitz, Oliver, Zeiser, Robert, Schemmer, Peter, Bruns, Helge, Eiermann, Thomas, Price, David A., Blum, Hubert E., Neumann‐Haefelin, Christoph, Thimme, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2014
Assuntos:
Hepatobiliary Malignancies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139003/
https://ncbi.nlm.nih.gov/pubmed/24002931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26731
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