Tetramer Enrichment Reveals the Presence of Phenotypically Diverse Hepatitis C Virus-Specific CD8(+) T Cells in Chronic Infection

Virus-specific CD8(+) T cells are rarely detectable ex vivo by conventional methods during chronic hepatitis C virus (HCV) infection. In this study, however, we were able to detect and characterize HCV-specific CD8(+) T cells in all chronically HCV genotype 1a-infected, HLA-A*02:01-positive patients...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Nitschke, Katja, Flecken, Tobias, Schmidt, Julia, Gostick, Emma, Marget, Matthias, Neumann-Haefelin, Christoph, Blum, Hubert E., Price, David A., Thimme, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301109/
https://ncbi.nlm.nih.gov/pubmed/25320295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02242-14
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