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Host and viral factors contributing to CD8+ T cell failure in hepatitis C virus infection

Virus-specific CD8+ T cells are thought to be the major anti-viral effector cells in hepatitis C virus (HCV) infection. Indeed, viral clearance is associated with vigorous CD8+ T cell responses targeting multiple epitopes. In the chronic phase of infection, HCV-specific CD8+ T cell responses are usu...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Neumann-Haefelin, Christoph, Spangenberg, Hans Christian, Blum, Hubert E, Thimme, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611762/
https://ncbi.nlm.nih.gov/pubmed/17828815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i36.4839
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