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Tumor-associated antigen specific CD8(+) T cells in hepatocellular carcinoma – a promising target for immunotherapy

Immunotherapy is a promising treatment option for patients with hepatocellular carcinoma (HCC). Indeed, CD8(+) T-cell responses against various tumor antigens occur in these patients. However, these antitumoral T cells show a severely impaired effector function. Several immunosuppressive mechanisms...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Schmidt, Nathalie, Flecken, Tobias, Thimme, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292268/
https://ncbi.nlm.nih.gov/pubmed/25941604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.954919
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