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Tumor-associated antigen specific CD8(+) T cells in hepatocellular carcinoma – a promising target for immunotherapy

Immunotherapy is a promising treatment option for patients with hepatocellular carcinoma (HCC). Indeed, CD8(+) T-cell responses against various tumor antigens occur in these patients. However, these antitumoral T cells show a severely impaired effector function. Several immunosuppressive mechanisms...

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書目詳細資料
發表在:Oncoimmunology
Main Authors: Schmidt, Nathalie, Flecken, Tobias, Thimme, Robert
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292268/
https://ncbi.nlm.nih.gov/pubmed/25941604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.954919
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