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Impact of Diet-Induced Obesity on Intestinal Stem Cells: Hyperproliferation but Impaired Intrinsic Function That Requires Insulin/IGF1

Nutrient intake regulates intestinal epithelial mass and crypt proliferation. Recent findings in model organisms and rodents indicate nutrient restriction impacts intestinal stem cells (ISC). Little is known about the impact of diet-induced obesity (DIO), a model of excess nutrient intake on ISC. We...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mah, Amanda T., Van Landeghem, Laurianne, Gavin, Hannah E., Magness, Scott T., Lund, P. Kay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138564/
https://ncbi.nlm.nih.gov/pubmed/24914941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1112
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