Mechanism of Action of Glucagon-Like Peptide-2 to Increase IGF-I mRNA in Intestinal Subepithelial Fibroblasts

IGF-I, a known secretory product of intestinal subepithelial myofibroblasts (ISEMFs), is essential for the intestinotropic effects of glucagon-like peptide-2 (GLP-2). Furthermore, GLP-2 increases IGF-I mRNA transcript levels in vitro in heterogeneous fetal rat intestinal cultures, as well as in vivo...

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Detaylı Bibliyografya
Asıl Yazarlar: Leen, Jason L. S., Izzo, Angelo, Upadhyay, Chandani, Rowland, Katherine J., Dubé, Philip E., Gu, Steven, Heximer, Scott P., Rhodes, Christopher J., Storm, Daniel R., Lund, P. Kay, Brubaker, Patricia L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2011
Konular:
Diabetes-Insulin-Glucagon-Gastrointestinal
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384785/
https://ncbi.nlm.nih.gov/pubmed/21159855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0822
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