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Insulin Regulates Glucagon-Like Peptide-1 Secretion from the Enteroendocrine L Cell

Insulin resistance and type 2 diabetes mellitus are associated with impaired postprandial secretion of glucagon-like peptide-1 (GLP-1), a potent insulinotropic hormone. The direct effects of insulin and insulin resistance on the L cell are unknown. We therefore hypothesized that the L cell is respon...

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Pubblicato in:Endocrinology
Autori principali: Lim, Gareth E., Huang, Guan J., Flora, Nina, LeRoith, Derek, Rhodes, Christopher J., Brubaker, Patricia L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393261/
https://ncbi.nlm.nih.gov/pubmed/18818290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0726
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