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Functional Role of Serotonin in Insulin Secretion in a Diet-Induced Insulin-Resistant State
The physiological role of serotonin, or 5-hydroxytryptamine (5-HT), in pancreatic β-cell function was previously elucidated using a pregnant mouse model. During pregnancy, 5-HT increases β-cell proliferation and glucose-stimulated insulin secretion (GSIS) through the Gα(q)-coupled 5-HT2b receptor (H...
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| Publicado no: | Endocrinology |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298319/ https://ncbi.nlm.nih.gov/pubmed/25426873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1687 |
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