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Benzoquinones as Inhibitors of Botulinum Neurotoxin Serotype A

Although botulinum neurotoxin serotype A (BoNT/A) is known for its use in cosmetics, it causes a potentially fatal illness, botulism, and can be used as a bioterror weapon. Many compounds have been developed that inhibit the BoNTA zinc-metalloprotease light chain (LC), however, none of these inhibit...

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Bibliographic Details
Main Authors: Bremer, Paul T., Hixon, Mark S., Janda, Kim D.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138410/
https://ncbi.nlm.nih.gov/pubmed/24984937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.06.004
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