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Benzylidene cyclopentenediones: First Irreversible Inhibitors against Botulinum Neurotoxin A’s Zinc Endopeptidase
A series of benzylidene cyclopentenedione-based inhibitors, acting through covalent modification of the active site of botulinum neurotoxin A light chain metalloprotease, are reported.
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818383/ https://ncbi.nlm.nih.gov/pubmed/19914829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.10.129 |
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