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Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1
MicroRNAs (miRNAs) play critical roles in a variety of biological processes through widespread effects on protein synthesis. Upon association with the miRNA-induced silencing complex (miRISC), miRNAs repress target mRNA translation and accelerate mRNA decay. Degradation of the mRNA is initiated by s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138323/ https://ncbi.nlm.nih.gov/pubmed/25035296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045302.114 |
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