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Control of Translation and miRNA-Dependent Repression by a Novel Poly(A) Binding Protein, hnRNP-Q

Translation control often operates via remodeling of messenger ribonucleoprotein particles. The poly(A) binding protein (PABP) simultaneously interacts with the 3′ poly(A) tail of the mRNA and the eukaryotic translation initiation factor 4G (eIF4G) to stimulate translation. PABP also promotes miRNA-...

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Detalhes bibliográficos
Main Authors: Svitkin, Yuri V., Yanagiya, Akiko, Karetnikov, Alexey E., Alain, Tommy, Fabian, Marc R., Khoutorsky, Arkady, Perreault, Sandra, Topisirovic, Ivan, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660254/
https://ncbi.nlm.nih.gov/pubmed/23700384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001564
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