Translational control of ERK signaling through miRNA/4EHP-directed silencing

MicroRNAs (miRNAs) exert a broad influence over gene expression by directing effector activities that impinge on translation and stability of mRNAs. We recently discovered that the cap-binding protein 4EHP is a key component of the mammalian miRNA-Induced Silencing Complex (miRISC), which mediates g...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jafarnejad, Seyed Mehdi, Chapat, Clément, Matta-Camacho, Edna, Gelbart, Idit Anna, Hesketh, Geoffrey G, Arguello, Meztli, Garzia, Aitor, Kim, Sung-Hoon, Attig, Jan, Shapiro, Maayan, Morita, Masahiro, Khoutorsky, Arkady, Alain, Tommy, Gkogkas, Christos, G, Stern-Ginossar, Noam, Tuschl, Thomas, Gingras, Anne-Claude, Duchaine, Thomas F, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5819943/
https://ncbi.nlm.nih.gov/pubmed/29412140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35034
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