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Challenges and opportunities in targeting the menin-MLL interaction
Menin is an essential co-factor of oncogenic MLL fusion proteins and the menin-MLL interaction is critical for development of acute leukemia in vivo. Targeting the menin-MLL interaction with small molecules represents an attractive strategy to develop new anticancer agents. Recent developments, incl...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138051/ https://ncbi.nlm.nih.gov/pubmed/24635524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.214 |
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