H3K4me3 breadth is linked to cell identity and transcriptional consistency

Trimethylation of Histone H3 at Lysine 4 (H3K4me3) is a chromatin modification known to mark the transcription start sites of active genes. Here we show that H3K4me3 domains that spread more broadly over genes in a given cell type preferentially mark genes essential for the identity and function of...

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Detalhes bibliográficos
Main Authors: Benayoun, Bérénice A., Pollina, Elizabeth A., Uçar, Duygu, Mahmoudi, Salah, Karra, Kalpana, Wong, Edith D., Devarajan, Keerthana, Daugherty, Aaron C., Kundaje, Anshul B., Mancini, Elena, Hitz, Benjamin C., Gupta, Rakhi, Rando, Thomas A., Baker, Julie C., Snyder, Michael P., Cherry, J. Michael, Brunet, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137894/
https://ncbi.nlm.nih.gov/pubmed/25083876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.027
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