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Epigenetic regulation of ageing: linking environmental inputs to genomic stability
Ageing is affected by both genetic and non-genetic factors. Here, we review the chromatin-based epigenetic changes that occur during ageing, the role of chromatin modifiers in modulating lifespan and the importance of epigenetic signatures as biomarkers of ageing. We also discuss how epigenome remod...
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| Publicado en: | Nat Rev Mol Cell Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4736728/ https://ncbi.nlm.nih.gov/pubmed/26373265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm4048 |
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