H3K4me3 breadth is linked to cell identity and transcriptional consistency

Trimethylation of Histone H3 at Lysine 4 (H3K4me3) is a chromatin modification known to mark the transcription start sites of active genes. Here we show that H3K4me3 domains that spread more broadly over genes in a given cell type preferentially mark genes essential for the identity and function of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Benayoun, Bérénice A., Pollina, Elizabeth A., Uçar, Duygu, Mahmoudi, Salah, Karra, Kalpana, Wong, Edith D., Devarajan, Keerthana, Daugherty, Aaron C., Kundaje, Anshul B., Mancini, Elena, Hitz, Benjamin C., Gupta, Rakhi, Rando, Thomas A., Baker, Julie C., Snyder, Michael P., Cherry, J. Michael, Brunet, Anne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137894/
https://ncbi.nlm.nih.gov/pubmed/25083876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.06.027
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