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Structural and Thermodynamic Analysis of PDZ–Ligand Interactions
Tiam-family guanine exchange proteins are activators of the Rho GTPase Rac1 and critical for cell morphology, adhesion, migration, and polarity. These modular proteins contain a variety of signaling domains, including a single postsynaptic density-95/discs large/zonula occludens-1 (PDZ) domain. Here...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137555/ https://ncbi.nlm.nih.gov/pubmed/21195225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381268-1.00004-5 |
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