CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.
The Nef gene product is a regulatory protein of HIV whose biological function is poorly understood. Nef has been thought to have a negative effect on viral replication in vitro but has been shown in studies with SIV to be necessary in the establishment of viraemia in vivo. In vitro studies in variou...
Furkejuvvon:
| Publikašuvnnas: | EMBO J |
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| Váldodahkkit: | , , , |
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Nature Publishing Group
1993
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| Fáttát: | |
| Liŋkkat: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8262036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb06186.x |
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