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CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals.

PCR was used to clone isolates of the human immunodeficiency virus type 1 (HIV-1) nef gene directly from peripheral blood leukocytes of HIV-1-infected individuals. A transient expression system with human CEM T cells was used to assess the effect of nef on CD4 antigen expression on the cell surface....

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Detalhes bibliográficos
Main Authors: Mariani, R, Skowronski, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46758/
https://ncbi.nlm.nih.gov/pubmed/8516299
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