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Pyrrolobenzodiazepines (PBDs) Do Not Bind to DNA G-Quadruplexes
The pyrrolo[2,1-c][1,4] benzodiazepines (PBDs) are a family of sequence-selective, minor-groove binding DNA-interactive agents that covalently attach to guanine residues. A recent publication in this journal (Raju et al, PloS One, 2012, 7, 4, e35920) reported that two PBD molecules were observed to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136862/ https://ncbi.nlm.nih.gov/pubmed/25133504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105021 |
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