Wordt geladen...
From Anthramycin to Pyrrolobenzodiazepine (PBD)‐Containing Antibody–Drug Conjugates (ADCs)
The pyrrolo[2,1‐c][1,4]benzodiazepines (PBDs) are a family of sequence‐selective DNA minor‐groove binding agents that form a covalent aminal bond between their C11‐position and the C2‐NH(2) groups of guanine bases. The first example of a PBD monomer, the natural product anthramycin, was discovered i...
Bewaard in:
| Gepubliceerd in: | Angew Chem Int Ed Engl |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2016
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215561/ https://ncbi.nlm.nih.gov/pubmed/27862776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201510610 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|