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ATR regulates hexavlent chromium-induced S-phase checkpoint through phosphorylation of SMC1
Hexavalent chromium (Cr[VI]) is an industrial waste product known to cause nasal and lung cancer in exposed workers. Intracellularly, Cr[VI] undergoes a series of enzymatic reductions resulting in the formation of reactive chromate intermediates and oxygen free radicals. These metabolites react with...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136750/ https://ncbi.nlm.nih.gov/pubmed/16876463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2006.06.007 |
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