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ATR regulates hexavlent chromium-induced S-phase checkpoint through phosphorylation of SMC1

Hexavalent chromium (Cr[VI]) is an industrial waste product known to cause nasal and lung cancer in exposed workers. Intracellularly, Cr[VI] undergoes a series of enzymatic reductions resulting in the formation of reactive chromate intermediates and oxygen free radicals. These metabolites react with...

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Bibliografski detalji
Glavni autori: Wakeman, Timothy P., Xu, Bo
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136750/
https://ncbi.nlm.nih.gov/pubmed/16876463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2006.06.007
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