Regulation of Intra-S Phase Checkpoint by Ionizing Radiation (IR)-dependent and IR-independent Phosphorylation of SMC3

Structure maintenance of chromosome 1 (SMC1) is phosphorylated by ataxia telangiectasia-mutated (ATM) in response to ionizing radiation (IR) to activate intra-S phase checkpoint. A role of CK2 in DNA damage response has been implicated in many previous works, but the molecular mechanism for its acti...

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Detalhes bibliográficos
Main Authors: Luo, Hao, Li, Yehua, Mu, Jung-Jung, Zhang, Jinglan, Tonaka, Toru, Hamamori, Yasuo, Jung, Sung Yun, Wang, Yi, Qin, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443663/
https://ncbi.nlm.nih.gov/pubmed/18442975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802299200
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