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PTIP Regulates 53BP1 and SMC1 at the DNA Damage Sites
Although PTIP is implicated in the DNA damage response, through interactions with 53BP1, the function of PTIP in the DNA damage response remain elusive. Here, we show that RNF8 controls DNA damage-induced nuclear foci formation of PTIP, which in turn regulates 53BP1 localization to the DNA damage si...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709350/ https://ncbi.nlm.nih.gov/pubmed/19414588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002527 |
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