Assessing Subunit Dependency of the Plasmodium Proteasome Using Small Molecule Inhibitors and Active Site Probes

[Image: see text] The ubiquitin-proteasome system (UPS) is a potential pathway for therapeutic intervention for pathogens such as Plasmodium, the causative agent of malaria. However, due to the essential nature of this proteolytic pathway, proteasome inhibitors must avoid inhibition of the host enzy...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Li, Hao, van der Linden, Wouter A., Verdoes, Martijn, Florea, Bogdan I., McAllister, Fiona E., Govindaswamy, Kavitha, Elias, Joshua E., Bhanot, Purnima, Overkleeft, Herman S., Bogyo, Matthew
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136710/
https://ncbi.nlm.nih.gov/pubmed/24918547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5001263
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki